Name: iNeuMab™ Anti-CD195 BBB Shuttle Antibody (NRZP-1022-ZP3697)
SKU: NRZP-1022-ZP3697
Rating: 5 (1 reviews)

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Humanized

Isotype

IgG1

Applications

Block; Inhib; In Vivo; FC

Relevant Diseases

Multiple Sclerosis

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CD195

Official Name

CCR5

Full Name

C-C Motif Chemokine Receptor 5

Alternative Names

C-C Motif Chemokine Receptor 5 (Gene/Pseudogene); Chemokine (C-C Motif) Receptor 5; HIV-1 Fusion Coreceptor; CC-CKR-5; ChemR13; CMKBR5; CCR-5; Chemokine (C-C Motif) Receptor 5 (Gene/Pseudogene); C-C Motif Chemokine Receptor 5 A159A; Chemokine Recptor CCR5 Delta32;

Publications