NeuroMab™ Anti-GARP Antibody(NRP-0422-P1640)

[CAT#: NRP-0422-P1640]

Functional antibody against Human, Cynomolgus Monkey GARP

Host Species:: Humanized

Species Reactivity:: Human; Cynomolgus Monkey

Applications:: FC; Inhib; Block; In Vitro; In Vivo

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Product Overview

Description

The antibody inhibits human Treg function in in vitro suppression assays. The antibody binding to GARP in the presence of TGF-β, cross-reactive with cynomolgus GARP-TGFβ1.

Species Reactivity

Human; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Humanized

Applications

FC; Inhib; Block; In Vitro; In Vivo

Relevant Diseases

Amyotrophic Lateral Sclerosis

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

GARP

Official Name

LRRC32

Full Name

Leucine Rich Repeat Containing 32

Alternative Names

Leucine Rich Repeat Containing 32; Glycoprotein A Repetitions Predominant; Transforming Growth Factor Beta Activator LRRC3; Leucine-Rich Repeat-Containing Protein 3; D11S833E; Garpin; GARP; LRRC32