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Creative Biolabs

NeuroMab™ Anti-Tau Oligomer Antibody(NRP-0422-P1753)

[CAT#: NRP-0422-P1753] Review(5) Q&As(3)

Functional antibody against Human Tau Oligomer

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; IHC; IF; In Vitro

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Product Overview

Description

The antibody is selective for pathological tau dimers and/or prefibrillar pathological tau oligomers.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; IHC; IF; In Vitro

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

TauOligomer

Alternative Names

MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
Our research focuses on Alzheimer's disease, we utilized it in in vitro experiments
The antibody shows excellent specificity and sensitivity to tau oligomers, which is crucial for our studies. It has significantly improved our ability to detect and quantify tau pathology, making our findings more reliable and reproducible.
user
Excellent
This antibody is outstanding for immunofluorescence applications
We've been able to visualize tau oligomers with high resolution and minimal background noise. The staining is bright and specific, making it easy to distinguish tau deposits. Additionally, the antibody performs well in WB, providing sharp, distinct bands.
user
Excellent
This has enhanced the accuracy of our studies on tauopathies
It has provided consistent results across various experiments, including WB and IHC. The antibody's ability to specifically recognize tau oligomers without cross-reacting with monomeric tau is particularly noteworthy.
user
Excellent
We've employed it in WB and IF with great success
The antibody provides clean, distinct bands in WB and bright, specific staining in IF. Its high affinity for tau oligomers has been critical for our work, allowing us to track tau aggregation and distribution accurately.
user
Excellent
In my experience, it performs exceptionally well
The antibody provides strong, specific signals with minimal background interference. It has significantly improved our ability to study tau oligomerization and its role in neurodegenerative diseases.
Q&As
What is the recommended dilution ratio for using the antibody in WB?
The recommended dilution ratio for the antibody, in Western blotting is typically 1:1000. However, optimal dilutions may vary depending on the specific conditions and the protein concentration in your samples. It is advisable to perform a preliminary dilution series to determine the best working concentration for your particular experimental setup. Always include appropriate positive and negative controls to validate your results.
Is there technical support available if I encounter issues in my experiments?
Yes, we offer comprehensive technical support for the antibody. Our team of experienced scientists is available to assist with any issues or questions you may have regarding the antibody's use in your experiments. We provide troubleshooting guidance, protocol optimization tips, and detailed product information to ensure successful outcomes. You can reach our technical support team via email, phone, or our online support portal.
Can I use the antibody in conjunction with other tau antibodies for multiplex analysis?
Yes, the antibody can be used in conjunction with other tau antibodies for multiplex analysis. Its high specificity for tau oligomers makes it an excellent candidate for co-labeling studies with antibodies targeting different tau forms or other neuronal markers. When designing multiplex experiments, ensure that the secondary antibodies used are compatible and that their fluorophores or detection methods do not overlap to avoid cross-interference. This approach allows for comprehensive analysis of tau pathology and its interactions within the neuronal environment.
For Research Use Only. Not For Clinical Use.
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