iNeuMab™ Anti-PSK9 Antibody (NRP-0422-P1592)

Name: iNeuMab™ Anti-PSK9 Antibody (NRP-0422-P1592)
SKU: NRP-0422-P1592
Rating: 5 (1 reviews)

[CAT#: NRP-0422-P1592]

Functional antibody against Human, Cynomolgus Monkey PCSK9

Host Species:: Chimeric

Species Reactivity:: Human; Cynomolgus Monkey

Applications:: FC; Inhib; In Vitro; In Vivo

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Product Overview

Description

Epitope mapping of NRP-0422-P1592 revealed binding at D192, R194, D238, D374, S376 in the catalytic domain of human PCSK9.

Immunogen

catalytic domain

Species Reactivity

Human; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Chimeric

Applications

FC; Inhib; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease; Stroke; Neuroinflammation

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

PSK9

Official Name

PCSK9

Full Name

Proprotein Convertase Subtilisin/Kexin Type 9

Alternative Names

Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9; NARC-1; NARC1; PC9; Convertase Subtilisin/Kexin Type 9 Preproprotein; Hypercholesterolemia; Autosomal Dominant 3; Neural Apoptosis Regulated Convertase 1; Neural Apoptosis-Regulated Convertase 1;