Creative Biolabs

Midbrain Neuron Differentiation Service

[CAT#: NRZP-1222-ZP14]

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Assay Overview


Creative Biolabs offers midbrain neuronal differentiation service to generate midbrain neuronal precursor cells from human pluripotent stem cell (hPSC)-derived neural progenitor cells (NPC). In conjunction with our midbrain maturation service, midbrain neuron precursors are further matured into midbrain neurons. The resulting midbrain neurons are a population of ≥ 15% TH-positive dopaminergic neurons; ≥ 90% class III β-tubulin-positive neurons; and < 10% GFAP-positive astrocytes. Cells derived using these products are versatile tools for modeling human neurodevelopment and disease, drug screening, toxicity testing, and cell therapy validation.
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Kits Overview

Differentiation kit for the generation of midbrain-patterned neuronal precursors from human ES and iPS cell-derived neural progenitor cells

Kit Features

Supports highly efficient generation of midbrain-like functional neurons from hPSC-derived neuronal precursors
Produces a population of TH-positive neurons (>15%) that can be maintained long term in culture
Supports neuronal activity for physiologically relevant results
Enables reproducible maturation of midbrain-type neuronal precursors derived from multiple human ES and iPS cell lines

Kit Components

NeuDiff™ Midbrain Neuron Differentiation Basal Medium, 80 mL
NeuDiff™ Midbrain Neuron Differentiation Supplement, 20 mL
For Research Use Only. Not For Clinical Use.
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