Duchenne Muscular Dystrophy (DMD) In Vitro Assay Service
Duchenne Muscular Dystrophy (DMD) presents a significant challenge to researchers seeking effective therapies. At Creative Biolabs, we understand the urgency and complexity of this disease. That's why we offer a comprehensive suite of cutting-edge in vitro, in vivo, and ex vivo assays designed to provide unparalleled insights into DMD's intricate mechanisms. Partner with Creative Biolabs and leverage our advanced platforms to drive your research forward. Contact us today to learn how we can support your DMD research goals.
Available In Vitro Models
Fig.1 DMD patients' iPSCs.1
Cell models | Details |
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DMD Patient-Derived iPSCs |
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3D iPSC-Derived Skeletal Muscle Model |
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Neuromuscular Circuit Model |
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Available DMD In Vitro Assays
Gain deeper insights into DMD with our comprehensive in vitro assay panel. Our assays deliver crucial readouts, including:
- Cell Viability Analysis: Determine the impact of treatments on muscle cell survival.
- Myotube Formation Analysis: Assess the ability of myoblasts to differentiate and form functional muscle fibers.
- Creatine Kinase (CK) Release Analysis: Quantify muscle damage through precise CK measurement.
- Contractile Function Analysis: Evaluate muscle strength and endurance using advanced techniques.
- Dystrophin Expression Analysis: Measure dystrophin protein levels to assess gene therapy efficacy.
- Inflammatory Markers Analysis: Analyze inflammatory responses in muscle tissue.
Accelerate your DMD research with our specialized CRO services. Leveraging state-of-the-art 3D in vitro models, we provide comprehensive testing solutions designed to drive breakthroughs from fundamental mechanism studies to effective drug development. Our advanced platforms deliver precise, physiologically relevant data, enabling you to optimize your therapeutic strategies. Contact us today to develop a customized service plan tailored to your specific research needs and accelerate your path to impactful discoveries.
Reference
- Budzińska, Marta, et al. "In Vitro Gene Therapy Using Human iPS-Derived Mesoangioblast-Like Cells (HIDEMs) Combined with Microdystrophin (μDys) Expression as the New Strategy for Duchenne Muscular Dystrophy (DMD) Experimental Treatment." International Journal of Molecular Sciences 25.22 (2024): 11869. Distributed under Open Access license CC BY 4.0, without modification.
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