- NeuroMab™ Anti-Tau Antibody,Clone NR2218P (Cat#: NRP-0422-P2275)
- NeuroMab™ Anti-Alpha Synuclein Antibody,Clone NR3861P (Cat#: NRP-0422-P614)
- NeuroMab™ Anti-Tau Antibody,Clone NR2946P (Cat#: NRP-0422-P1686)
- NeuroMab™ Anti-TNFα BBB Shuttle Antibody,Clone NR3088P (Cat#: NRZP-1022-ZP4105)
- NeuroMab™ Anti-ApoC3 BBB Shuttle Antibody,Clone NR1616P (Cat#: NRZP-1022-ZP3505)
- NeuroMab™ Anti-GD2 Antibody,Clone NR3007P (Cat#: NRZP-1222-ZP767)
- NeuroMab™ Anti-F-Spondin/SPON1 Antibody, Clone N24875P (CBP11839) (Cat#: NRZP-0822-ZP4740)
- Tau Monoclonal Antibody (AT120, HT7 and BT2 clone) (Cat#: NK-2106-P008)
- NeuroMab™ Anti-Tau Antibody,Clone NR2944P (Cat#: NRP-0422-P1684)
- Mouse Anti-SCN5A Monoclonal Antibody (CBP708) (Cat#: NAB-0720-Z2720)
- iNeu™ Retinal Pigment Epithelial Cells (RPE) (Cat#: NRZP-0323-ZP92)
- Human Dental Pulp Stem Cells (Cat#: NRZP-1122-ZP113)
- Rat Olfactory Ensheathing Cells (Cat#: NRZP-1122-ZP162)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Human Brain Astroblastoma U-87 MG (Cat#: NCL2110P117)
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- Green Fluorescent Tau SH-SY5Y cell Line (Cat#: NCL2110P219)
- Human Brain Vascular Pericytes (Cat#: NCL-21P6-015)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Beta Amyloid (1-40), Aggregation Kit, TTF Assay (Cat#: NRZP-0323-ZP199)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- AAV2/2Retro-CAG-DIO-EGFP-2A-TetTox-pA [Neural Tracing] (Cat#: NTA-2012-ZP303)
- AAV-mDLX-CRE-tdTomato (Cat#: NRZP-0622-ZP721)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- AAV-EF1a-mCherry-flex-dtA (Cat#: NRZP-0622-ZP616)
- AAV2/9-hEF1a-DIO-mCherry-P2A-TetTox-WPRE-pA (Cat#: NTA-2012-ZP268)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroPro™ Anti-IDS BBB Shuttle Protein, HIRMab-IDS (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein, HIRMab-GDNF (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein, HIRMab-NAGLU (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein, HIRMab-IDUA (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein, cTfRMAb-IDUA (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein, HIRMab-PON1 (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein, 8D3-IL-1RA (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein, cTfRMAb-GDNF (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-ASA BBB Shuttle Protein, HIRMab-ASA (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein, cTfRMAb-TNFR (Cat#: NRZP-0423-ZP501)
Ischemic Stroke In Vitro Assay
Creative Biolabs offers a comprehensive suite of advanced In Vitro assays specifically tailored to study ischemic stroke. These assays utilize neuronal cell cultures or brain tissue samples to simulate the ischemic environment and study the impact on various cellular processes. By manipulating key parameters, such as oxygen and glucose availability, researchers can mimic the conditions observed during ischemic stroke and evaluate cellular responses.
Our Ischemic Stroke Assay Models
Creative Biolabs offers a range of Ischemic Stroke In Vitro Assay models that faithfully recapitulate the pathophysiological features of ischemic stroke. These models incorporate both neuronal and non-neuronal cell types to simulate the complex interactions within the ischemic microenvironment.
Our commonly used assay models for ischemic stroke research include:
![Neuronal Cell Culture Models](static/img/ischemic-stroke-in-vitro-assay-1.jpg)
Neuronal Cell Culture Models
Neuronal cell culture models, such as primary neurons or neuronal cell lines, form the cornerstone of ischemic stroke research. Culturing these cells under conditions that mimic oxygen and glucose deprivation enables the study of cellular responses and the identification of neuroprotective compounds.
![Co-culture Models](static/img/ischemic-stroke-in-vitro-assay-2.jpg)
Co-culture Models
Co-culture models involve the combination of neurons with astrocytes, microglia, or endothelial cells, enable the examination of cell-cell interactions and the contribution of non-neuronal cells to ischemic injury.
![3D Brain Organoids](static/img/ischemic-stroke-in-vitro-assay-3.jpg)
3D Brain Organoids
We provide cutting-edge 3D brain organoid models that closely resemble the cellular diversity and organization of the brain tissue. These organoids can be subjected to ischemia-like conditions, offering a unique platform for studying the impact of ischemic stroke on neuronal networks.
![Blood-Brain Barrier (BBB) Models](static/img/ischemic-stroke-in-vitro-assay-4.jpg)
Blood-Brain Barrier (BBB) Models
Dysfunction of the BBB is a key feature of ischemic stroke. Creative Biolabs offers advanced BBB models that faithfully reproduce the barrier properties, allowing for investigations into BBB integrity, transport mechanisms, and drug permeability in the context of ischemic stroke.
Our Ischemic Stroke Assay Readouts
Our ischemic stroke assays can provide important readouts that help researchers understand the underlying mechanisms of ischemic stroke and evaluate potential therapeutic interventions. Our studies encompass several areas to analyze the different stages of the cell death process and the potential recovery of damaged neurons. Some specific assays and analyses we perform include:
- Caspase 3-7 Activation
- LDH Release
- Neurite Outgrowth Study
- Neural Cell Viability
- Mitochondrial Damage
- Oxidative Stress
Assay Workflow
Creative Biolabs follows a rigorous workflow to ensure the robustness and reproducibility of Ischemic Stroke In Vitro Assays.
Options for Collaborating with Creative Biolabs
-
Order ischemic stroke cell models for use in your lab
If you are interested in ordering ischemic stroke cell models and perform the assay in your lab, we offer a convenient and flexible supply of ischemic stroke research cell models. -
Outsource your experiments to us
We offer a dependable and efficient service that involves collaborative experiment design to meet your specific needs. Please contact us today to explore the possibilities of collaborating with our organization.
Cat. | Product Name |
NCL-0723-ZP8 | Rat Primary Neurons |
NCL-0723-ZP9 | Mouse Primary Neurons |
NRZP-0723-ZP1 | iNeu™ Neuron, Astrocyte, Microglia Co-culture Kit |
NCL-2103-P187 | Human 3D Blood Brain Barrier Model, Ready-to-Use |
NRZP-0822-ZP250 | Human iPSC-derived Neural Forebrain Organoids |
NRZP-0822-ZP251 | Human iPSC-derived Neural Midbrain Organoids |