Fragile X Syndrome In Vitro Assay Service

Fragile X Syndrome (FXS) is a genetic disorder characterized by intellectual disabilities, behavioral challenges, and physical features. As a leading expert in the field of neuroscience, Creative Biolabs is committed to providing innovative solutions for studying and understanding FXS. Our state-of-the-art In Vitro assays offer a powerful platform to investigate the underlying molecular mechanisms of this disorder, enabling advancements in therapeutic development and personalized medicine.

Our Fragile X Syndrome Assay Models

At Creative Biolabs, we harness the power of induced pluripotent stem cells (iPSCs) derived from patients carrying an FMR1 mutation to faithfully replicate the pathophysiology of Fragile X syndrome. This innovative model allows researchers to delve into the intricate molecular and cellular intricacies of the disease, thereby gaining valuable insights. Furthermore, we also offer control cell lines without the mutation for comparative analysis.

Our Fragile X Syndrome Assays

To comprehensively assess the effects of potential therapeutics and understand the molecular mechanisms underlying Fragile X syndrome, it is essential to employ reliable and sensitive readout systems in In Vitro assays. Creative Biolabs offers a wide range of readout options that enable researchers to obtain accurate and quantitative data.

• Dendritic spine morphology analysis. Fragile X syndrome is characterized by abnormal dendritic spine development, and assessing changes in spine density and morphology can provide insights into the impact of potential therapeutic interventions on neuronal connectivity.
• Synaptic plasticity analysis: A key cellular process affected in Fragile X syndrome, can be evaluated using electrophysiological techniques such as patch-clamp recordings. This allows researchers to investigate alterations in synaptic transmission and excitability, providing valuable information about the functional consequences of Fragile X syndrome and the efficacy of potential therapeutic strategies.

Workflow of Fragile X Syndrome In Vitro Assay

At Creative Biolabs, we have developed a streamlined workflow for Fragile X syndrome In Vitro assays to ensure accurate and efficient experimental procedures. Our workflow includes the following key steps:

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Options for Collaborating with Creative Biolabs

• Order Fragile X Syndrome assay models for use in your lab
  If you are interested in ordering Fragile X Syndrome assay models and perform the assay in your lab, we offer a convenient and flexible supply of Fragile X Syndrome research cell models. Please contact info@creative-biolabs.org for availability and price information.

Cat.	Product Name
NCL-0723-ZP10	Human iPSC-Derived Neural Stem Cells - Fragile X Syndrome Patient, FMR1 Mutation
NCL-0723-ZP11	Human iPSC-Derived Neural Stem Cells - Fragile X Syndrome Patient
NCL-0723-ZP12	Human iPSC-Derived Neural Stem Cells - Healthy

• Outsource your experiments to us
  We offer a dependable and efficient service that involves collaborative experiment design to meet your specific needs. Please contact us today to explore the possibilities of collaborating with our organization.