MS In Vitro Assay

Creative Biolabs provides comprehensive and groundbreaking in vitro assay solutions for Multiple Sclerosis (MS), enabling researchers to unravel the intricate mechanisms that underlie this complex neurological disorder.

In Vitro Models of MS at Creative Biolabs

At Creative Biolabs, we recognize the crucial role of cell models in replicating the intricate cellular environment of MS. Our vast array of well-established cell lines, including primary human neural cells, oligodendrocytes, and immune cells, accurately mimic the pathological conditions observed in MS patients.

MS In Vitro Assays at Creative Biolabs

• Cytokine Release Assay

Our cutting-edge multiplex platforms allow for the precise quantification of cytokines, chemokines, and other immune mediators. This enables us to delineate the inflammatory milieu associated with MS and assess the impact of potential therapeutics on immune responses.

• Antigen Presentation Assays

These assays evaluate the ability of antigen-presenting cells to stimulate T-cell responses. They help researchers understand how immune cells recognize and respond to myelin antigens in MS.

• Lipopolysaccharide (LPS)-induced Neuroinflammation Assay

Studying LPS-induced inflammation in MS-related immune cells can provide insights into the exaggerated immune responses and neuroinflammation observed in MS lesions. It can help researchers understand the mechanisms by which immune cells contribute to demyelination and neuronal damage in the context of inflammation.

• Nitric Oxide Production Assay

Nitric oxide is a signaling molecule that plays a role in neuroinflammation and oxidative stress, which are key aspects of MS pathology. Measuring nitric oxide levels helps researchers understand the balance between its physiological and pathological roles in MS.

• Myelination Assay

Preserving myelin sheaths is a fundamental therapeutic goal in MS. Through innovative myelination assays, we replicate the process of myelin formation using co-cultures of oligodendrocytes and neurons. This platform facilitates the screening of compounds that enhance myelination and promote neural repair.

• Myelin Phagocytosis Assay

These assays assess the ability of immune cells to phagocytose myelin, providing insights into the mechanisms of demyelination and potential therapeutic interventions.

Advantages of In Vitro Assay for MS at Creative Biolabs

Creative Biolabs' cutting-edge in vitro cell models play a pivotal role in facilitating neurotoxicity assessments and pharmaceutical screenings. Our versatile in vitro assays establish a robust framework for dissecting the intricate pathways of multiple sclerosis (MS) pathogenesis, pinpointing promising therapeutic targets, and appraising potential interventions.

With our regulatory expertise and extensive experience in neuroscience research, Creative Biolabs stands ready to propel your MS research endeavors to new heights. Please feel free to contact us for more details.