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Creative Biolabs
Product

Mouse Anti-Human HSC70 Monoclonal Antibody (CBP3691)

[CAT#: NAB201228LS]

Anti-HSC70 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB

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Product Overview

Description

Hsp70 is a member of the Hsp family of highly conserved proteins that play a role in a number of important functions. Their synthesis is increased upon environmental stress. They function by acting as molecular chaperones, facilitating protein refolding and preventing protein aggregation. It has been reported that extracellular Hsp70 also exhibits immunomodulatory effects on innate and acquired immunity.

Immunogen

Purified recombinant human HSC70 fragment (1-1755bp of Acc. Y00371)

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP3691

Applications

WB

Application Notes

WB (0.5-2.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

Batch Dependent

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

HSPA8

Official Name

HSPA8

Full Name

Heat shock 70kDa protein 8

Alternative Names

Heat shock 70 kDa protein 8; Hsc70; HSC71; HSP71; HSP73; HSPA10; HSPA8

Gene ID

3312(Human); 15481(Mouse); 24468(Rat)

Uniprot ID

P11142(Human); P63017(Mouse); P63018(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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