NeuroMab™ Anti-ACT BBB Shuttle Antibody(NRZP-1222-ZP1028)
[CAT#: NRZP-1222-ZP1028]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- Neut; Inhib
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SPECIFIC INQUIRY
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Description
Integrins are ubiquitous cell-surface heterodimers that are exploited by pathogens and toxins, including leukotoxins that target β 2 integrins on phagocytes. The Bordetella adenylate cyclase toxin (ACT) uses the α M β 2 integrin as a receptor. The neutralizing antibody epitopes map to ACT residues involved in α M binding, providing the basis for antibody-mediated attachment inhibition.
Species Reactivity
Human
Host Species
Mouse
Applications
Neut; Inhib
Relevant Diseases
Alzheimer's Disease
Target
Target
ACT
Official Name
ACT
Full Name
Antichymotrypsin
Alternative Names
ACT; Activator of cAMP responsive element modulator (CREM); Antichymotrypsin
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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