NeuroMab™ Anti-Alpha Synuclein Antibody(NRP-0422-P619)

Product Overview

Description

NRP-0422-P619 preferentially bind α-synuclein aggregates or fibrils over the monomeric form of α-synuclein. NRP-0422-P619 does only bind to coated full length α-synuclein but not to any of the four tested truncations.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Applications

WB; ELISA; IHC; In Vitro; In Vivo

Relevant Diseases

Parkinson's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

AlphaSynuclein

Official Name

SNCA

Full Name

Alpha-synuclein

Alternative Names

SNCA; NACP; PARK1; PARK4; PD1; synuclein alpha

Gene ID

6622 (Human); 20617 (Mouse)

Uniprot ID

P37840

Product Pictures

ELISA

Figure 1 Recombinant human α-synuclein antibodies against different epitopes.

Recombinant full-length and truncated α-synuclein were coated onto ELISA plates at the same coating concentration (20 μg/ml).

ELISA

Figure 2 Recombinant human α-synuclein antibody binds α-synuclein but not β- and γ-synuclein in a direct ELISA.

Recombinant α-, β- and γ-synuclein coated onto ELISA plates at the same coating concentration (2 μg/ml) together with recombinant human α-synuclein antibody or pan-synuclein antibody Incubation.

Publications