iNeuMab™ Anti-Alpha Synuclein Antibody (NRP-0422-P611)

Q: How does the specificity of Clone NR3855P?

Clone NR3855P exhibits exceptional specificity for alpha-synuclein, distinguishing it from other proteins with high accuracy. This antibody has been rigorously tested to ensure minimal cross-reactivity with other synuclein family members, such as beta-synuclein and gamma-synuclein. Researchers can rely on Clone NR3855P for precise detection of alpha-synuclein in complex biological samples, reducing the likelihood of false positives and enhancing the validity of their findings.

Q: What are the storage conditions for the antibody to ensure its stability and longevity?

To ensure the stability and longevity of the antibody, it should be stored at -20°C upon receipt. For short-term storage (up to one month), it can be kept at 4°C. Avoid repeated freeze-thaw cycles as they can degrade the antibody's performance. Proper storage conditions will maintain the antibody’s efficacy and reliability for long-term use.

Q: Are there any recommended protocols for using Clone NR3855P in immunohistochemistry?

Yes, we provide detailed protocols for using Clone NR3855P in immunohistochemistry. For optimal results, we recommend using a 1:200 to 1:500 dilution range, depending on the tissue type and antigen retrieval method. Standard protocols include antigen retrieval using citrate buffer (pH 6.0) and incubation with the antibody at 4°C overnight. These guidelines help achieve robust staining and reproducible results.

Product Overview

Description

The antibody has a high affinity for aggregated forms of α-synuclein and a low affinity for monomeric forms of α-synuclein. The antibody is useful in the diagnosis of neurodegenerative diseases.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

DB; ELISA; FC; IHC; In Vitro

Relevant Diseases

Parkinson's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

AlphaSynuclein

Official Name

SNCA

Full Name

Alpha-synuclein

Alternative Names

SNCA; NACP; PARK1; PARK4; PD1; synuclein alpha

Gene ID

6622 (Human); 20617 (Mouse)

Uniprot ID

P37840

Publications

Publications (0)

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Customer Reviews and Q&As

Customer Reviews Average Customer Ratings Overall

5.0

Excellent

The antibody's specificity and sensitivity are outstanding, providing clear and distinct staining

It has significantly enhanced our ability to detect alpha-synuclein aggregation in brain tissues, leading to more reliable results.

Excellent

Its high affinity for alpha-synuclein ensures reproducible and consistent results

The antibody provides excellent specificity and minimal background noise, allowing us to obtain clear and precise data. It has greatly facilitated our research on the cellular mechanisms underlying Parkinson's disease.

Excellent

An invaluable tool for our research

The antibody produced sharp and clear images, allowing us to visualize alpha-synuclein distribution accurately. Its performance has been consistently reliable.

Excellent

Its consistent performance and reliability have made it a favorite in our lab

It offers high sensitivity and specificity. We have consistently obtained accurate and reproducible results.

Excellent

It has been a reliable and effective tool in our research

Using the antibody for flow cytometry has greatly enhanced our ability to analyze alpha-synuclein expression in various cell types. The antibody's specificity and low background staining make it ideal for our studies.

Q&As

How does the specificity of Clone NR3855P?

Clone NR3855P exhibits exceptional specificity for alpha-synuclein, distinguishing it from other proteins with high accuracy. This antibody has been rigorously tested to ensure minimal cross-reactivity with other synuclein family members, such as beta-synuclein and gamma-synuclein. Researchers can rely on Clone NR3855P for precise detection of alpha-synuclein in complex biological samples, reducing the likelihood of false positives and enhancing the validity of their findings.

What are the storage conditions for the antibody to ensure its stability and longevity?

To ensure the stability and longevity of the antibody, it should be stored at -20°C upon receipt. For short-term storage (up to one month), it can be kept at 4°C. Avoid repeated freeze-thaw cycles as they can degrade the antibody's performance. Proper storage conditions will maintain the antibody’s efficacy and reliability for long-term use.

Are there any recommended protocols for using Clone NR3855P in immunohistochemistry?

Yes, we provide detailed protocols for using Clone NR3855P in immunohistochemistry. For optimal results, we recommend using a 1:200 to 1:500 dilution range, depending on the tissue type and antigen retrieval method. Standard protocols include antigen retrieval using citrate buffer (pH 6.0) and incubation with the antibody at 4°C overnight. These guidelines help achieve robust staining and reproducible results.