NeuroMab™ Anti-CD171 BBB Shuttle Antibody(NRZP-1022-ZP3536)
[CAT#: NRZP-1022-ZP3536]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; FC; In Vitro; In Vivo
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG
Applications
WB; ELISA; FC; In Vitro; In Vivo
Relevant Diseases
Tumor
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
CD171
Official Name
L1CAM
Full Name
L1 cell adhesion molecule
Alternative Names
L1CAM; CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1; L1 cell adhesion molecule
Product Pictures
FuncS
Figure 1: Measurement of cellular uptake of mAb L1CAM mAb 9.3 on Skov3ip cells.
FuncS
Figure 2: Measurement of cellular uptake of L1CAM mAb 9.3 and OV52.24 on Skov3ip cells.
FuncS
Figure 3: Measurement of cellular uptake of L1CAM mAb 9.3 and OV52.24 on Skov3ip cells using confocal laser scanning microscopy.
FuncS
Figure 4: Measurement and comparison of cellular uptake of antibodies L1CAM mAb 9.3, OV52.24, 5G3 and UJ127.11 on Skov3ip cells.
FuncS
Figure 5: Comparison of cellular uptake of L1CAM mAb 9.3, OV52.24, 5G3 and UJ127.11 on Skov3ip cells.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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