NeuroMab™ Anti-CXCL10 BBB Shuttle Antibody(NRZP-1022-ZP3430)
[CAT#: NRZP-1022-ZP3430]
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; IHC; Inhib; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Isotype
IgG
Applications
WB; ELISA; IHC; Inhib; In Vitro; In Vivo
Relevant Diseases
Neuroinflammation
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
CXCL10
Official Name
CXCL10
Full Name
chemokine (C-X-C motif) ligand 10
Alternative Names
gIP-10; INP10; 10 kDa interferon gamma-induced protein; IP-10; C-X-C motif chemokine 10; 1-73; Small-inducible cytokine B10; IFI10; Gamma-IP10; SCYB10; crg-2; C7; mob-1
Product Pictures
ELISA
Figure 1 is a graph showing the activity of antibodies IP 10.1 and IP 10.44 inhibiting free serum IP-12.
FuncS
Figure 2 is a graph showing the activity of antibodies IP 10.1 and IP 10.46 in reducing NK cell frequency.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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