NeuroMab™ Anti-EGFR BBB Shuttle Antibody(NRZP-1022-ZP3456)
[CAT#: NRZP-1022-ZP3456]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; FC; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Immunogen
extracellular domain of CLDN-5
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
WB; ELISA; FC; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease; Pain; Multiple Sclerosis
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
EGFR
Official Name
EGFR
Full Name
Epidermal Growth Factor Receptor
Alternative Names
Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian);
Product Pictures
FuncS
Figure 1 shows the results for MDCKII/hCLDN-5.
FuncS
Figure 2 shows the results for MDCKII/cCLDN-5.
FuncS
Figure 3 shows the results for MDCKII/mCLDN-5.
FuncS
Figure 4 shows the results using MDCKII/mock.
FuncS
Figure 5 shows the results for MDCKII/hCLDN-5.
FuncS
Figure 6 shows the results for MDCKII/cCLDN-5.
FuncS
Figure 7 shows the results for MDCKII/mCLDN-5.
Publications
Publications (0)
Neural Antibodies
Cell Assay Reagents
For Research Use Only. Not For Clinical Use.
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