iNeuMab™ Anti-GARP BBB Shuttle Antibody (NRZP-1022-ZP3031)

Name: iNeuMab™ Anti-GARP BBB Shuttle Antibody (NRZP-1022-ZP3031)
SKU: NRZP-1022-ZP3031
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP3031]

Host Species:: Humanized

Species Reactivity:: Human; Cynomolgus Monkey

Applications:: FC; Inhib; Block; In Vitro; In Vivo

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Inquiry

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Humanized

Applications

FC; Inhib; Block; In Vitro; In Vivo

Relevant Diseases

Amyotrophic Lateral Sclerosis

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

GARP

Official Name

LRRC32

Full Name

Leucine Rich Repeat Containing 32

Alternative Names

Leucine Rich Repeat Containing 32 ; Glycoprotein A Repetitions Predominant ; Transforming Growth Factor Beta Activator LRRC3; Leucine-Rich Repeat-Containing Protein 3; D11S833E ; Garpin ; GARP ; LRRC32

Publications