NeuroMab™ Anti-IL-6 BBB Shuttle Antibody (NRZP-1022-ZP2897)
- Host Species:
- Mouse
- Species Reactivity:
- Human; Cynomolgus Monkey
- Applications:
- ELISA; Block; Inhib; In Vitro
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 shows the competition ELISA analysis of BA001 and anti-IL-6 antibodies.
Figure 2 shows the inhibition of IL-6/sIL6R-induced Stat3 phosphorylation in THP-1 cells by increasing the concentration of anti-IL-6 monoclonal antibody. Data were normalized based on western blot of total Stat3.
Figure 3 shows the phosphorylation of Stat3 in THP-1 cells stimulated with IL-6/sIL-6R by various anti-IL6 mAbs including 003, BA399, BA399-2 and BA399-9 (A) using 100 ng/mL IL- The inhibitory effect of 6.
Figure 4 shows the effect of serially diluted anti-IL-6 monoclonal antibodies CNTO136, BA399, BA399-2, BA399-9 on the production of serum amyloid A by HepG2 cells stimulated with human IL-6, sIL-6R and IL-1b Inhibition at 24 hours.
Figure 5 After serial dilution of anti-IL-6 monoclonal antibodies CNTO136, BA399, BA399-2, BA399-9, HepG2 cells stimulated with human IL-6, sIL-6R and IL-1b inhibited serum amyloid A at 48 Hour.
Figure 6 shows the inhibition of IL-6-induced proliferation of DS-1 cells by anti-IL-6 monoclonal antibodies BA001, BA399, BA436, BA802, BA808, BA840, BA848 and BA890 at 48 hours.
Figure 7 shows the inhibition of IL-6-induced proliferation of DS-1 cells by anti-IL-6 monoclonal antibodies BA001, BA399, BA436, BA802, BA808, BA840, BA848 and BA890 at 96 hours.
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