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Creative Biolabs
Product

NeuroMab™ Anti-Notch1 Antibody, Clone N24824 (CBP14855)

[CAT#: NRZP-0922-ZP3544]

Host Species:
Rabbit
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; IF; FC

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Product Overview

Description

The NeuroMab™ anti-Notch1 antibody detects intracellular epitopes between 2450 and 2550 amino acids of human Notch1. It recognizes both the full-length (~300 KDa) and the NTM region (~120 KDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence and the intracellular domain (NICD). The antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.

Expression Host

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro2498 of human Notch1.

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Rabbit

Isotype

Rabbit IgG

Clone Number

CBP14855

Applications

WB; IF; FC
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

NOTCH1

Official Name

NOTCH1

Full Name

Notch1

Alternative Names

AOVD1; Translocation-associated notch protein TAN-1; NEXT; hN1; AOS5; NICD; Notch 1; Neurogenic locus notch homolog protein 1; TAN1

Gene ID

4851(Human)

Uniprot ID

P46531(Human)
Publications

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For Research Use Only. Not For Clinical Use.
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