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Creative Biolabs

NeuroMab™ Anti-PDGFRA BBB Shuttle Antibody(NRZP-1022-ZP4040)

[CAT#: NRZP-1022-ZP4040]

Host Species:
Human
Species Reactivity:
Human
Applications:
FC

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Isotype

IgG1

Applications

FC

Relevant Diseases

Glioblastoma
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

PDGFRA

Official Name

PDGFRA

Full Name

platelet-derived growth factor receptor A

Alternative Names

alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA BCR fusion; PDGF-R-alpha; platelet-derived growth factor receptor; alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein; RHEPDGFRA
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