NeuroMab™ Anti-SERT BBB Shuttle Antibody(NRZP-1222-ZP1080)
[CAT#: NRZP-1222-ZP1080]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- In Vitro
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. Creative Biolabs has developed a BBB shuttle antibody platform that actively transports these large biomolecules across the BBB via receptor-mediated transcytosis (RMT). The engineered BBB shuttle antibody is believed to significantly increase the uptake of therapeutic molecules in the brain.
Species Reactivity
Human
Host Species
Mouse
Applications
In Vitro
Relevant Diseases
Depression; Anxiety; Obsessive Compulsive Disorder
Target
Target
SERT
Official Name
SLC6A4
Full Name
Serotonin transporter
Alternative Names
SLC6A4; 5-HTT; 5HTT; HTT; OCD1; SERT; SERT1; hSERT; Solute Carrier Family 6 (neurotransmitter transporter); member 4; solute carrier family 6 member 4; 5-HTTLPR
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
For Research Use Only. Not For Clinical Use.
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Tracers
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Cell Assay Reagents
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
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