NeuroMab™ Anti-Tau Antibody(NRP-0422-P1773)
[CAT#: NRP-0422-P1773]
Functional antibody against Human Tau
- Host Species:
- Mouse; Humanized
- Species Reactivity:
- Human
- Applications:
- WB; DB; ELISA; IHC; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The monoclonal antibody binds selectively to pathological Tau, useful for treating tauopathies, neurodegenerative diseases associated with pathological aggregation of Tau.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse; Humanized
Applications
WB; DB; ELISA; IHC; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Product Pictures
IHC
Figure 4 shows immunohistochemistry (IHC) of human brain sections with mAb005 (also known as RAA7) and mAb037 for the indicated brain regions and their disease status (ND vs AD), Braak stage (I-VI) and ID markers Dye on top.
IHC
Figure 5 shows IHC staining of the four indicated PSP brain tissues with mAb005 and mAb037, showing a positive mAb005 signal for each tissue.
FuncS
Figure 6 shows the binding affinity of original mouse clone mAb037 and humanized mAb037 to AD and ND brain homogenates.
FuncS
Figure 7 shows Tau and DAPI staining with and without mAb005 and mAb037.
WB
Figure 1 shows Western blot analysis of HT7, mAb005, and mAb037 on rTg4510 and WT brain lysates.
WB
Figure 2 shows Western blot analysis of HT7, mAb005, and mAb037 on AD and ND brain lysates.
WB
Figure 3 shows Western blot analysis of sarcosyl soluble and insoluble fractions in AD brains by HT7, mAb005, and mAb037.
Publications
Publications (0)
Neural Genes
Kits
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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