NeuroMab™ Mouse Anti-Apolipoprotein E/APOE Monoclonal Antibody (CBP2520)

Product Overview

Description

Mouse Anti-Human Apolipoprotein E/APOE Monoclonal IgG1, Kappa

Immunogen

ApoE (E-8) is a mouse monoclonal antibody targeting epitope mapping
Between the amino acids 293-318 near the C-terminus of apoE of human origin.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, Kappa

Clone Number

CBP2520

Applications

WB; IP; IF; ELISA

Application Notes

WB: 1/100
IP:
IF: 1/50-1/500
ELISA: 1/30-1/3000

Relevant Diseases

Alzheimer's Disease

Research Areas

Neuroregeneration

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1845

Product Properties

Form

Liquid

Formulation

PBS, < 0.1% sodium azide, 0.1% gelatin

Preservatives

YES

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at 4°C, **DO NOT FREEZE**.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Apo E

Official Name

Apoe

Full Name

Apolipoprotein E

Alternative Names

APOE; AD2; APO-E; LDLCQ5; LPG; apolipoprotein E; ApoE4

Gene ID

348 (Human); 11816 (Mouse)

Uniprot ID

P02649 (Human); P08226 (Mouse)

References

1. Muñoz, S.S., et al. 2018. The serine protease HtrA1 contributes to the
formation of an extracellular 25-kDa apolipoprotein E fragment that
stimulates neuritogenesis. J. Biol. Chem. 293: 4071-4084.
2. Mouchard, A., et al. 2019. ApoE-fragment/Ab heteromers in the brain of
patients with Alzheimer's disease. Sci. Rep. 9: 3989.

Publications