Creative Biolabs

Mouse Anti-ADAR Monoclonal Antibody (AB134)

[CAT#: NAB2007FY1689]

Amyotrophic Lateral Sclerosis,
Parkinson's, Alzheimer's and Huntington's diseases

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB; IF

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Description
Neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease and Huntington's disease The result of the gradual loss of neuron structure and function, Causes neuron death. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
AB134
Applications
IHC; WB; IF
Application Notes
IHC: 1:500-1:1000
WB: 1 µg/ml
IF: 2-10 µg/ml
Relevant Diseases
Alzheimer's Disease; Huntington's Disease; Parkinson's Disease; Amyotrophic Lateral Sclerosis
Form
Liquid
Formulation
PBS, pH 7.2, 40% glycerol
Preservatives
0.02% Sodium azide
Concentration
1 mg/ml
Purification
Protein A purified
Shipping
Gel Pack
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
ADAR
Official Name
ADAR
Full Name
Adenosine Deaminase, RNA Specific
Alternative Names
Adenosine Deaminase, RNA Specific; 136 KDa Double-Stranded RNA-Binding Protein; Interferon-Inducible Protein 4; Interferon-Induced Protein 4; K88DSRBP; ADAR1; DRADA; DSRAD; IFI-4; P136; G1P1
Gene ID
103(Human); 56417(Mouse); 81635(Rat)
Uniprot ID
P55265(Human); Q99MU3(Mouse); P55266(Rat)
For Research Use Only. Not For Clinical Use.
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