NeuroMab™ Anti-AQP4 BBB Shuttle Antibody(NRZP-1022-ZP3672)
[CAT#: NRZP-1022-ZP3672]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; IHC; Inhib; CDC; In Vitro
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
ELISA; IHC; Inhib; CDC; In Vitro
Relevant Diseases
Epilepsy; Stroke; Glioblastoma
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
AQP4
Official Name
AQP4
Full Name
Aquaporin 4
Alternative Names
AQP4; Aquaporin 4
Product Pictures
ELISA
Figure 1 is a graph showing the affinity of anti-aquaporin monoclonal antibodies when using CHO cells expressing hAQP4M1 or hAQP4-M23.
Figure 1 shows the results for the C9401 antibody.
ELISA
Figure 2 shows the affinity of the C9401 chimeric antibody.
FuncS
Figure 3 is a graph showing the inhibitory effect of C9401 chimeric antibody on NMO-IgG complement-dependent cytotoxicity.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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