NeuroMab™ Anti-Leptin Antibody(NRP-0422-P1627)
[CAT#: NRP-0422-P1627]
Functional antibody against Human Leptin
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- ELISA; Neut; IHC; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The anti-leptin monoclonal antibody is screened by using in-house prepared scFv phage display human antibody library. The antibody increases leptin transcription in brown and epididymal adipose tissue, reduces circulating leptin, and reduces high fat diet effects on brown adipose tissue.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Applications
ELISA; Neut; IHC; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease; Obesity
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Product Pictures
FuncS
Figure 1. Antibody therapy reduces body weight.
FuncS
figure 2. Antibody therapy reduces food intake.
FuncS
Figure 3. Antibody therapy increases leptin transcription in brown and epididymal adipose tissue.
FuncS
Figure 4. Antibody therapy reduces circulating leptin.
FuncS
Figure 5. Antibody treatment reduces the effect of a high-fat diet on brown adipose tissue.
Publications
Publications (0)
Kits
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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