NeuroMab™ Anti-Leptin BBB Shuttle Antibody(NRZP-1022-ZP3020)
[CAT#: NRZP-1022-ZP3020]
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- ELISA; Neut; IHC; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Applications
ELISA; Neut; IHC; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease; Obesity
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
Leptin
Official Name
LEP
Full Name
Leptin
Alternative Names
LEP; LEPD; OB; OBS; leptin
Product Pictures
FuncS
Figure 1. Antibody therapy reduces body weight.
FuncS
figure 2. Antibody therapy reduces food intake.
FuncS
Figure 3. Antibody therapy increases leptin transcription in brown and epididymal adipose tissue.
FuncS
Figure 4. Antibody therapy reduces circulating leptin.
FuncS
Figure 5. Antibody treatment reduces the effect of a high-fat diet on brown adipose tissue.
Publications
Publications (0)
Kits
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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