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Creative Biolabs
Product

Mouse Anti-AQP4 Monoclonal Antibody (CBP6741)

[CAT#: NAB2007FY1690]

Amyotrophic Lateral Sclerosis,
Parkinson's, Alzheimer's and Huntington's diseases

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB

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Product Overview

Description

Neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease and Huntington's disease The result of the gradual loss of neuron structure and function, Causes neuron death. This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Epitope

Binds to an located within the peptide sequence FKRRFKEAFS

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6741

Applications

IHC; WB

Application Notes

IHC: 1:200-1:500
WB: 1 µg/ml

Relevant Diseases

Alzheimer's Disease; Huntington's Disease; Parkinson's Disease; Amyotrophic Lateral Sclerosis
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

0.5 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

AQP4

Official Name

AQP4

Full Name

Aquaporin 4

Alternative Names

Aquaporin 4; Mercurial-Insensitive Water Channel; MIWC; WCH4; Aquaporin Type4; Aquaporin-4; AQP-4

Gene ID

361(Human); 11829(Mouse); 25293(Rat)

Uniprot ID

P55087(Human); P55088(Mouse); P47863(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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