NeuroMab™ Anti-ABCG2 BBB Shuttle Antibody(NRZP-1022-ZP3623)

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; IF; Inhib; FC; In Vitro; Apop

Relevant Diseases

Alzheimer's Disease

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

ABCG2

Official Name

ABCG2

Full Name

ATP Binding Cassette Subfamily G Member 4

Alternative Names

ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group); ATP-Binding Cassette; Sub-Family G (WHITE); Member 2 (Junior Blood Group); Placenta-Specific ATP-Binding Cassette Transporter; Mitoxantrone Resistance-Associated Protein; Breast Cancer Resistance Protein; Urate Exporter; CDw338; BCRP1; ABCP; BCRP; MXR; Multi Drug Resistance Efflux Transport ATP-Binding Cassette Sub-Family G (WHITE) Member 2; ATP-Binding Cassette; Sub-Family G (WHITE); Member 2; ATP-Binding Cassette Sub-Family G Member 2;

Publications