NeuroMab™ Anti-ABCG2(NRP-0422-P921)

Product Overview

Description

The monoclonal antibody targeting ABCG2 is the only ABCG2 monoclonal antibodies using 618-633 as an antigenic determinant and clearly targeting the extracellular loop domain formed between the C-terminal TM5 and TM6. By disrupting the formation of ABCG2 dimer via the disulfide bond of cysteine at position 603, the antibodies further disrupt the formation of ABCG2 homologous oligomeric complex.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; IF; Inhib; FC; In Vitro; Apop

Relevant Diseases

Alzheimer's Disease

Product Properties

Preservatives

BSA Free

Concentration

1mg/mL

Endotoxin Level

Regualr Endotoxin < 5EU/mg
Low endotoxin < 1EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

ABCG2

Official Name

ABCG2

Full Name

ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group)

Alternative Names

ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group); ATP-Binding Cassette; Sub-Family G (WHITE); Member 2 (Junior Blood Group); Placenta-Specific ATP-Binding Cassette Transporter; Mitoxantrone Resistance-Associated Protein; Breast Cancer Resistance Protein; Urate Exporter; CDw338; BCRP1; ABCP; BCRP; MXR; Multi Drug Resistance Efflux Transport ATP-Binding Cassette Sub-Family G (WHITE) Member 2; ATP-Binding Cassette; Sub-Family G (WHITE); Member 2; ATP-Binding Cassette Sub-Family G Member 2;