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Creative Biolabs

NeuroMab™ Anti-CXCL10 BBB Shuttle Antibody(NRZP-1022-ZP3429)

[CAT#: NRZP-1022-ZP3429]

Host Species:
Human
Species Reactivity:
Human
Applications:
WB; ELISA; IHC; Inhib; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Isotype

IgG

Applications

WB; ELISA; IHC; Inhib; In Vitro; In Vivo

Relevant Diseases

Neuroinflammation
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

CXCL10

Official Name

CXCL10

Full Name

chemokine (C-X-C motif) ligand 10

Alternative Names

gIP-10; INP10; 10 kDa interferon gamma-induced protein; IP-10; C-X-C motif chemokine 10; 1-73; Small-inducible cytokine B10; IFI10; Gamma-IP10; SCYB10; crg-2; C7; mob-1
Product Pictures
ELISA

Figure 1 is a graph showing the activity of antibodies IP 10.1 and IP 10.44 inhibiting free serum IP-11.

FuncS

Figure 2 is a graph showing the activity of antibodies IP 10.1 and IP 10.45 in reducing NK cell frequency.

Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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