Product
NeuroMab™ Anti-Dopamine D2 receptor BBB Shuttle Antibody, Clone N186/29
[CAT#: NRZP-0423-ZP96]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-DRD2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 211-374 (cytoplasmic, long form) of rat Dopamine D2 receptor (also known as Drd2, accession number P61169)
Mouse: 100% identity (164/164 amino acids identical)
Human: 92% identity (152/164 amino acids identical)
>80% identity with Short form
<25% identity with Dopamine D3 receptor
Mouse: 100% identity (164/164 amino acids identical)
Human: 92% identity (152/164 amino acids identical)
>80% identity with Short form
<25% identity with Dopamine D3 receptor
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N186/29
Applications
WB; IHC; ICC
Application Notes
Reacts with both Long and Short forms;Does not cross-react with Dopamine D3 receptor
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
DRD2
Official Name
DRD2
Full Name
Dopamine D2 receptor
Alternative Names
DRD2; D2DR; D2R; dopamine receptor D2
Uniprot ID
P61169
Product Pictures
IHC
Fig. 1 Adult rat striatum immunohistochemistry.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
