NeuroMab™ Anti-GluN2B BBB Shuttle Antibody(NRZP-1222-ZP1054)
[CAT#: NRZP-1222-ZP1054]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- Block; Inhib; In Vitro
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
N-methyl-D-aspartate receptors (NMDARs) are critically involved in basic brain functions and neurodegeneration as well as tumor invasiveness. Targeting specific subtypes of NMDARs with distinct activities has been considered an effective therapeutic strategy for neurological disorders and diseases. This inhibitory antibody recognizes the amino terminal domain of the GluN2B subunit and increases the population of the non-active conformational state.
Species Reactivity
Human
Host Species
Mouse
Applications
Block; Inhib; In Vitro
Relevant Diseases
Alzheimer's Disease; Parkinson's Disease
Target
Target
GRIN2B
Official Name
GRIN2B
Full Name
Glutamate [NMDA] receptor subunit epsilon-2
Alternative Names
GRIN2B; GluN2B; MRD6; NMDAR2B; NR2B; hNR3; EIEE27; glutamate ionotropic receptor NMDA type subunit 2B; NR3
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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