NeuroMab™ Anti-Tau BBB Shuttle Antibody(NRZP-1022-ZP3072)
[CAT#: NRZP-1022-ZP3072]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
WB; ELISA; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
Tau
Official Name
MAPT
Full Name
Tau Protein
Alternative Names
MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Product Pictures
WB
Figure 1 Western blotting (WB) analysis of general Tau antibody display in brain lysates from Alzheimer's disease (AD) and matched control donors.
ELISA
Figure 2 Tau capture ELISA.
FuncS
Figure 3 shows the pharmacokinetics in mice following a single 10mg/kg intravenous or intraperitoneal injection of anti-Tau antibody.
FuncS
Figure 4 shows that the change over time is flat in macaques following a single IV injection of 50 mg/kg of specific antibodies.
Publications
Publications (0)
Neural Genes
Neural Antibodies
Kits
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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