Mouse Anti-Human GGT1 Monoclonal Antibody (CBP4258)

[CAT#: NAB210128LS]

Anti-GGT1 Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human

Applications:: WB; IHC-P

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Product Overview

Description

GGT1 is a transferase that plays a key role in the gamma-glutamyl cycle. GGT1 is abundantly expressed in liver and kidney. Its involvement in glutathione metabolism makes it an important regulator of the oxidative stress in the central nervous system, as well as in other tissues. GGT1 is also a known marker for apoptosis. Importantly, elevated levels of GGT1 correlates with breast cancer tumor progression and resistance to chemotherapy, suggesting GGT1 as a candidate for cancer prognosis marker.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4258

Applications

WB; IHC-P

Application Notes

WB (0.5-5.0 µg/mL); IHC-P (1.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.