Mouse Anti-amyloid a-beta Monoclonal Antibody (CBP6651)
[CAT#: NAB2007FY1512]
Mouse Monoclonal to amyloid a-beta
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IF; IHC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Alzheimer's disease (AD) is a serious and increasingly common age-related dementia characterized by the formation of senile plaques, which are the extracellular accumulation of insoluble proteins. Another characteristic of AD is the formation of neurofibrillary tangles inside neurons. The main component of senile plaques is β-amyloid, also known as Aβ, a major form of peptide with a length of 42 or 40 amino acids. The Aβ peptide is obtained by proteolysis from a larger protein film lozalized, called amyloid precursor protein (APP). Due to certain point mutations in the APP gene and mutations in presenilin and other genes, the deposition of Aβ increases. The presence of certain alleles of the ApoE gene also increases the possibility of progression to AD.
Immunogen
1-42 Human amyloid Aβ epitope is sequence 1-16
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP6651
Applications
WB; IF; IHC
Application Notes
WB: 1:1000-1:2000
IF/IHC: 1:1000
IF/IHC: 1:1000
Product Properties
Form
Liquid
Formulation
50% PBS, 50% glycerol
Preservatives
5mM NaN3
Concentration
1 mg/ml
Shipping
Gel Pack
Storage
Stable at 4°C for one year, for longer term store at -20°C
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Publications
Publications (0)
Kits
Neural Antibodies
Neural Genes
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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