Tel:
Fax:
Email:
Creative Biolabs

Mouse Anti-amyloid a-beta Monoclonal Antibody (CBP6651)

[CAT#: NAB2007FY1512]

Mouse Monoclonal to amyloid a-beta

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; IF; IHC

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Inquiry

SPECIFIC INQUIRY

inquiry
Size:
Conjugation:
Endotoxin:
Purity:
Engineering:
Product Overview

Description

Alzheimer's disease (AD) is a serious and increasingly common age-related dementia characterized by the formation of senile plaques, which are the extracellular accumulation of insoluble proteins. Another characteristic of AD is the formation of neurofibrillary tangles inside neurons. The main component of senile plaques is β-amyloid, also known as Aβ, a major form of peptide with a length of 42 or 40 amino acids. The Aβ peptide is obtained by proteolysis from a larger protein film lozalized, called amyloid precursor protein (APP). Due to certain point mutations in the APP gene and mutations in presenilin and other genes, the deposition of Aβ increases. The presence of certain alleles of the ApoE gene also increases the possibility of progression to AD.

Immunogen

1-42 Human amyloid Aβ epitope is sequence 1-16

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP6651

Applications

WB; IF; IHC

Application Notes

WB: 1:1000-1:2000
IF/IHC: 1:1000
Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Stable at 4°C for one year, for longer term store at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

APP

Official Name

APP

Full Name

Amyloid Precursor Protein

Alternative Names

APP; AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; amyloid beta precursor protein; preA4

Gene ID

351 (Human); 11820 (Mouse); 54226 (Rat)

Uniprot ID

P05067 (Human); P12023 (Mouse); P08592 (Rat)
Publications

Publications (0)

gift-card

Related Products
Neural Genes
Kits
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
Product
Hot Products
Fill out this form for a quote Inquiry Form Send Inquiry
webinar

The Spectrum of Stem Cell-Based Neuronal Models and Their Fit for Purpose

2:00 PM–3:00 PM EST, December 12, 2024

REGISTER NOW
Inquiry Basket
compare

Send inquiry