iNeu™ Microglia AD APOE E4/E4 Kit, 11993, Disease Model
[CAT#: NCL-7P031]
Female, APOE 4/4, Alzheimer's Disease (AD)
- Species:
- Human
- Applications:
- Cell Assay
- Cell Types:
- Astrocyte
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Cell Kit
APOE RS429358: C/C
APOE RS7412: C/C
APOE Genotype: 4/4
TREM2 (P.R47H) RS7593268: C/C
CD33 RS12459419: C/C
APOE RS429358: C/C
APOE RS7412: C/C
APOE Genotype: 4/4
TREM2 (P.R47H) RS7593268: C/C
CD33 RS12459419: C/C
Cell Types
Astrocyte
Applications
Cell Assay
Application Notes
Normal CNS Functions
Synaptic remodeling and pruning
Neurotransmitter homeostasis
Neural network communication
Blood-brain barrier support
Regulation of CNS blood flow
CNS metabolism
Disease CNS Functions
Reactive astrogliosis and CNS inflammation
Neurodegenerative disease
Neuropsychiatric disease
Alexander disease and leukodystrophies
Multiple sclerosis and autoimmune inflammatory disorders
Infectious disease
Synaptic remodeling and pruning
Neurotransmitter homeostasis
Neural network communication
Blood-brain barrier support
Regulation of CNS blood flow
CNS metabolism
Disease CNS Functions
Reactive astrogliosis and CNS inflammation
Neurodegenerative disease
Neuropsychiatric disease
Alexander disease and leukodystrophies
Multiple sclerosis and autoimmune inflammatory disorders
Infectious disease
Species
Human
Properties
Size
1 Vial: ≥ 1 x 10^6 cells/vial
Components
Cryopreserved iNeu Microglia AD APOE E4/E4, 11993
50ml iNeu Glial Base Medium
0.5ml iNeu Microglia Supplement A (100x)
0.5ml iNeu Microglia Supplement B (100x)
2 x 1ml iNeu Neural Supplement C (25X)
iNeu Microglia Quick Guide
Additional reagents required; see Quick Guide
50ml iNeu Glial Base Medium
0.5ml iNeu Microglia Supplement A (100x)
0.5ml iNeu Microglia Supplement B (100x)
2 x 1ml iNeu Neural Supplement C (25X)
iNeu Microglia Quick Guide
Additional reagents required; see Quick Guide
Tissue Source
Fibroblast
Age
<18
Mycoplasma Testing
The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details
Target
APOE
Official Name
CACNA1C
Alternative Names
Calcium Voltage-Gated Channel Subunit Alpha1 C; Calcium Channel; L Type; Alpha-1 Polypeptide; Isoform 1; Cardiac Muscle; Calcium Channel; Voltage-Dependent; L Type; Alpha 1C Subunit; CACNL1A1; CCHL1A1; CACH2; CACN2; Voltage-Gated L-Type Calcium Channel Cav1.2 Alpha 1 Subunit; Splice Variant 10*; Calcium Channel; Cardic Dihydropyridine-Sensitive; Alpha-1 Subunit;
Donor Information
Gender
Female
Donor Health
Healthy
Ethnicity
Caucasian
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
