NeuroMab™ Anti-CD133 BBB Shuttle Antibody(NRZP-1022-ZP3382)

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; IF; ELISA; IHC

Relevant Diseases

Glioma

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CD133

Official Name

PROM1

Full Name

CD133 antigen

Alternative Names

PROM1; AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4; prominin 1

Product Pictures

Figure 1 shows Figures depicting CD133 staining of selected tumor cores from Multitumor TMA (MTU951, Biomax) stained with CD133 (mAb 133-3, mAb 47-10, 293C3, or AC133) - as indicated.

Figure 2 shows Figures depicting CD133 staining of selected tumor cores from Multitumor TMA (MTU951, Biomax) stained with CD133 (mAb 133-3, mAb 47-10, 293C3, or AC133) - as indicated.

Publications