Neuron related Calcium Assay Services

Neuronal calcium assays are a technique used to study neuronal activity by monitoring changes in calcium ion concentrations within neurons. We provide services for an assortment of calcium assays in neurons and more, guaranteeing the highest standard of scientific rigor, analysis, and communication. To learn more about our products and services, submit a project inquiry or request pricing, please contact us.

Introduction

Calcium ions are important molecules in intracellular signaling. As second messengers, they are involved in the regulation of a variety of biological processes, including neurotransmitter release, synaptic plasticity, and neuronal excitability. In the resting state, the concentration of calcium ions in neurons is usually maintained between 50-100 nM. Upon activation, ions flood into the cell, and the concentration of calcium ions increases significantly. For this reason, a deep understanding of the mechanism of action of calcium ions in neurons is of great importance for elucidating the working principle of the nervous system.

We can perform calcium assays in the following models:

• Cloned channels and receptors
• Brain neuron cultures
• Ex vivo brain slices
• Human iPSC-Derived neurons

Calcium Assays of Neurons

• Calcium Imaging Assay

Neuronal calcium imaging technology is a valuable tool for monitoring neuronal activity. This technology visualizes the changes in calcium ion concentrations in neurons. It uses special fluorescent dyes or calcium ion indicators to convert changes in calcium ion concentrations in neurons into changes in fluorescence intensity, thereby achieving real-time monitoring of neuronal activity. The ability to monitor neuronal calcium in this way provides a powerful tool for neuroscience research by allowing researchers to evaluate the roles of native proteins and the effects of potential treatments on calcium signaling.

• Calcium Flux & cAMP Assay

Our state-of-the-art calcium flux and cAMP assays are designed to provide precise and reliable measurements of intracellular calcium and cyclic adenosine monophosphate (cAMP) levels, enabling researchers to gain deeper insights into cellular signaling pathways and physiological responses. Backed by decades of expertise, our services offer robust performance and powerful analysis. Partner with us to harness the power of our cutting-edge technologies and elevate your research capabilities.

Calcium Assay-Related Products

Intracellular calcium is a critical factor in the induction of synaptic activity and the activation of signal transduction pathways. Functional imaging of calcium is a vital technology in neuroscience research, providing a measure of neuronal activity. Our product pipeline includes a variety of research tools designed to assist you in measuring calcium activity.