Rabbit Anti-PAK4 / PAK5 / PAK6 Monoclonal Antibody (CBP1923)

Name: Rabbit Anti-PAK4 / PAK5 / PAK6 Monoclonal Antibody (CBP1923)
SKU: NAB-08-PZ975
Rating: 5 (1 reviews)

[CAT#: NAB-08-PZ975]

Rabbit Monoclonal Antibody to PAK4 / PAK5 / PAK6 (phospho S474 / S560 / S602)

Host Species:: Rabbit

Species Reactivity:: Mouse; Rat; Human

Applications:: WB; FC

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Serine 474 of Human PAK4, Serine 602 of PAK5, and Serine 560 of PAK6.

Species Reactivity

Mouse; Rat; Human

Clonality

Monoclonal

Host Species

Rabbit

Isotype

IgG

Clone Number

CBP1923

Applications

WB; FC

Application Notes

Assay dependent

Research Areas

Neurogenesis

Pathways

Neurogenesis Signaling

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Purification

Protein A/G purified

Purity

>95%

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Notes: avoid repeated freeze-thaw cycles.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

PAK4; PAK5; PAK6

Official Name

PAK4; PAK5; PAK6

Full Name

Serine/threonine-protein kinase PAK 4/Serine/threonine-protein kinase PAK 5/Serine/threonine-protein kinase PAK 6

Alternative Names

Serine/threonine-protein kinase PAK 4 is an enzyme that in humans is encoded by the PAK4 gene.

PAK4 is one of six members of the PAK family of serine/threonine kinases which are divided into group I (PAK1; PAK2 and PAK3) and group II (PAK4; PAK6 and PAK5/7). PAK4 localizes in sub-cellular domains of the cytoplasm and nucleus. PAK4 regulates cytoskeleton remodeling; phenotypic signaling and gene expression; and affects directional motility; invasion; metastasis; and growth. Similar to PAK1; PAK4-signaling dependent cellular functions also regulate both physiologic and disease processes such as cancer as PAK4 is overexpressed and/or hyperstimulated in human cancer; at-large.

Publications