iNeuMab™ Anti-SALM2 synaptic adhesion-like molecule BBB Shuttle Antibody (NRZP-0423-ZP373)

Name: iNeuMab™ Anti-SALM2 synaptic adhesion-like molecule BBB Shuttle Antibody (NRZP-0423-ZP373)
SKU: NRZP-0423-ZP373
Rating: 5 (1 reviews)

[CAT#: NRZP-0423-ZP373]

Species Reactivity:: Rat; Mouse; Human

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Inquiry

Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-LRFN1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Fusion protein amino acids 551-766 (C-terminus) of mouse SALM2 (also known as synaptic adhesion-like molecule 2, leucine rich repeat and fibronectin type III domain containing 1, accession number Q460M4)
Human: 87% identity (195/222 amino acids identical)
<55% identity with other SALM's

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG1

Research Areas

CAMs

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

LRFN1

Official Name

LRFN1

Full Name

SALM2/LRFN1

Alternative Names

Leucine Rich Repeat And Fibronectin Type III Domain Containing 1 ;SALM2 ;Leucine-Rich Repeat And Fibronectin Type III Domain-Containing Protein 1 ;Synaptic Adhesion-Like Molecule ;KIAA1484 ;CTC-246B18.8 ;LRFN1