iNeuMab™ Anti-WAVE1/SCAR BBB Shuttle Antibody (NRZP-0423-ZP472)
[CAT#: NRZP-0423-ZP472]
- Species Reactivity:
- Rat; Mouse; Human
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Wave 1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide amino acids 477-498 (CQVIPASEPKRHPSTLPVISDAR) of human WAVE1 (also known as Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Verprolin homology domain-containing protein 1, KIAA0269, WASF1 and SCAR1, accession number Q92558)
Rat: 95% identity (21/22 amino acids identical)
Mouse: 95% identity (21/22 amino acid identical)
<50% identity with WASF3
Rat: 95% identity (21/22 amino acids identical)
Mouse: 95% identity (21/22 amino acid identical)
<50% identity with WASF3
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Wave 1
Official Name
WASF1
Full Name
WAVE1/SCAR
Alternative Names
WASF1; SCAR1; WAVE; WAVE1; WAS protein family member 1; WASP family member 1; NEDALVS
Uniprot ID
Q92558
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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