Anti-Wave 1 Monoclonal Antibody (CBP3893)
[CAT#: NAB2012456LS]
Anti-Wave 1 Monoclonal Antibody [HRP]
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat; Drosophila
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Organ morphogenesis can occur through cellular response to extracellular signals that alter actin dynamics. Wiskott-Aldrich syndrome protein-family verprolin homologous protein 1 (WAVE1) is an actin-interacting protein involved in brain morphogenesis. WAVE1 interacts with Arp (actin-related proteins) 2/3 to regulate the cytoskeleton. WAVE proteins mediate lamellipodia formation and are critical for normal CNS myelination. WAVE1 can be phosphorylated by Cdk5 to downregulate Arp2/3 complex-dependent actin polymerization.
Immunogen
This monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 477-498 of human Wave1/Wasp family 1 protein.
Species Reactivity
Human; Rat; Drosophila
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP3893
Applications
WB; IHC-P
Application Notes
WB (1.0-5.0 µg/mL); IHC-P (5.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties
Form
Liquid
Formulation
50% glycerol in aqueous buffered solutions with preservatives.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon receipt, the antibody solution should be stored undiluted at-20°C, and protected from prolonged exposure to light.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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