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Creative Biolabs

Anti-CD284 Monoclonal Antibody (CBP3909)

[CAT#: NAB2012487LS]

Anti-CD284 Monoclonal Antibody [Biotin]

Host Species:
Mouse
Species Reactivity:
Human; Guinea Porcine
Applications:
FC

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Product Overview

Description

TLR4, also known as CD284, is a 110 kD protein which is expressed on monocytes/macrophages, endothelial cells, and at low levels on B cells and granulocytes. In association with a secretory molecule, MD2, TLR4 has been recognized as critical for host recognition of bacterial LPS. HTA125 antibody is useful for flow cytometric analysis and is able to block LPS-induced cytokine production.

Immunogen

Ba/F3 cell line expressing human TLR4

Species Reactivity

Human; Guinea Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3909

Applications

FC

Application Notes

FCM (≤2.0 µg per million cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD284

Official Name

TLR4

Full Name

Toll-like receptor 4

Alternative Names

TLR4; Toll-like receptor 4

Gene ID

7099(Human); 21898(Mouse); 29260(Rat)

Uniprot ID

O00206(Human); Q9QUK6(Mouse); Q9QX05(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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