iNeuMab™ Anti-Flrt3 BBB Shuttle Antibody (NRZP-0423-ZP105)
[CAT#: NRZP-0423-ZP105]
- Species Reactivity:
- Mouse
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-FLRT3 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 29-526 (extracellular domain) of mouse Flrt3 (also known as Leucinerich repeat transmembrane protein FLRT3, Fibronectin-like domain-containing leucine-rich transmembrane protein 3, KIAA1469 and UNQ856/PRO1865, accession number Q8BGT1)
Rat: 99% identity (496/498 amino acids identical)
Human: 96% identity (480/498 amino acids identical)
>50% identity with Flrt1 and Flrt2
Rat: 99% identity (496/498 amino acids identical)
Human: 96% identity (480/498 amino acids identical)
>50% identity with Flrt1 and Flrt2
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
FLRT3
Official Name
FLRT3
Full Name
Flrt3
Alternative Names
FLRT3; HH21; fibronectin leucine rich transmembrane protein 3
Uniprot ID
Q8BGT1
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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