iNeuMab™ Anti-NSD3 BBB Shuttle Antibody (NRZP-0423-ZP312)
[CAT#: NRZP-0423-ZP312]
- Species Reactivity:
- Human; Rat; Mouse
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-WHSC1L1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 21-251 (N-terminus) of human NSD3 (also known as Nuclear SET domain-containing protein 3, Histone-lysine N-methyltransferase, Wolf-Hirschhorn syndrome candidate 1-like protein 1, WHSC1-like protein 1, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, WHSC1L1, Protein whistle and DC28, accession number Q9BZ95)
Mouse: 92% identity (214/231 amino acids identical)
Rat: 90% identity (208/231 amino acids identical)
<50% identity with NSD1 and NSD2
Mouse: 92% identity (214/231 amino acids identical)
Rat: 90% identity (208/231 amino acids identical)
<50% identity with NSD1 and NSD2
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Research Areas
Epigenetics
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
WHSC1L1
Official Name
NSD3
Full Name
NSD3
Alternative Names
NSD3; pp14328; WHSC1L1; WHISTLE; Wolf-Hirschhorn syndrome candidate 1-like 1; nuclear receptor binding SET domain protein 3; KMT3G; KMT3F
Uniprot ID
Q9BZ95
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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