iNeuMab™ Anti-Synapsin-III BBB Shuttle Antibody (NRZP-0423-ZP405)
[CAT#: NRZP-0423-ZP405]
- Species Reactivity:
- Human; Rat; Mouse
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Synapsin III BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 76-417 (actin-binding and synaptic-vesicle binding domains) of human Synapsin-III (also known as Synapsin-3 and SYN3, accession number O14994)
Rat: 94% identity (322/342 amino acids identical)
Mouse: 94% identity (321/342 amino acids identical)
>60% identity with Synapsin-1 and Synapsin-II
Rat: 94% identity (322/342 amino acids identical)
Mouse: 94% identity (321/342 amino acids identical)
>60% identity with Synapsin-1 and Synapsin-II
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Synapsin III
Official Name
SYN3
Full Name
Synapsin-3
Alternative Names
SYN3; synapsin III
Uniprot ID
O14994
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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