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Creative Biolabs

NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P810)

[CAT#: NRP-0422-P810] Review(5) Q&As(3)

A functional antibody raised against Human, Mouse TREM2.

Host Species:
Mouse
Species Reactivity:
Human; Mouse
Applications:
FC; ELISA; Block; In Vitro; In Vivo; Antagonist

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Product Overview

Description

The antibody specifically binds to a human triggering receptor expressed on myeloid cells 2 (TREM2) and useful in preventing, reducing risk, or treating an individual in need.

Immunogen

Mouse Fc Fused Human TREM2 ECD

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Applications

FC; ELISA; Block; In Vitro; In Vivo; Antagonist

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

TREM2

Official Name

TREM2

Full Name

Triggering receptor expressed on myeloid cells 2

Alternative Names

TREM2; Triggering receptor expressed on myeloid cells 2

Gene ID

54209(Human)

Uniprot ID

Q9NZC2(Human)
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
Outstanding
We used it in immunohistochemistry and found it to be highly specific with minimal background staining. The quality is consistent, and we’ve had excellent results with our tissue samples.
user
Excellent
It provided specific staining
We’ve used this antibody in our flow cytometry experiments, and it has proven to be effective in labeling TREM2-expressing cells. The staining was strong and reproducible, making it a reliable tool for our cell sorting applications.
user
Excellent
High-quality results
The antibody provided bright and specific staining in our brain tissue samples, and we experienced no cross-reactivity with other proteins.
user
Excellent
It provided robust and specific labeling
We used it for ELISA assays and found it to be highly sensitive and specific for detecting TREM2 levels in various biological samples. It’s become our go-to antibody for TREM2 research.
user
Excellent
A valuable asset in our research
We’ve had great success with this antibody in our studies of microglia. The antibody provides clear and specific labeling, which has been invaluable for our research into microglial function and TREM2 expression.
Q&As
Can the antibody be used for flow cytometry?
Yes, the antibody is suitable for flow cytometry. It is designed to effectively label TREM2-expressing cells, allowing for accurate analysis and sorting. Ensure that your cells are properly prepared and that the antibody is used at the recommended concentration for optimal staining.
What type of secondary antibodies work best with the antibody?
For optimal results, use secondary antibodies that are compatible with the primary antibody. For immunohistochemistry and Western blotting, we recommend using secondary antibodies conjugated to HRP or fluorescent dyes, depending on your detection method. Ensure that the secondary antibody is from a species different from that of the primary antibody.
How do I perform a positive control experiment with this antibody?
To validate the performance of the antibody, use a known TREM2-expressing cell line or tissue as a positive control. This will help confirm that the antibody is binding specifically to TREM2 and providing the expected staining or signal in your assays.
For Research Use Only. Not For Clinical Use.
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