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Creative Biolabs

Mouse Anti-Human BMP-10 Monoclonal Antibody (CBP3730)

[CAT#: NAB201289LS]

Anti-BMP-10 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Neut

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Product Overview

Description

Bone morphogenetic protein 10 (BMP-10) was originally cloned from the embryonic heart, and expression data indicate that it plays a key role in the formation of embryonic heart trabeculae. BMP-10 shares>98% amino acid sequence identity among human, mouse and rat orthologs. BMP is a member of the transforming growth factor beta (TGF-beta) superfamily. BMP-10 is synthesized as an inactive precursor BMP10 precursor (about 60 kD), and processed into active BMP-10 (about 14 kD) by proprotein convertase. Furin is the main invertase responsible for the production of BMP-10.

Immunogen

Recombinant Human BMP-10

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP3730

Applications

Neut

Application Notes

Neut (4-20 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

0.2 µm filtered in PBS, pH 7.2, containing no preservative.

Concentration

Batch Dependent

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Endotoxin level is <0.01 EU/µg of the protein (<0.001 ng/µg of the protein) as determined by the LAL test.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

BMP 10

Official Name

BMP10

Full Name

Bone morphogenetic protein 10

Alternative Names

BMP10; entrez:27302; bone morphogenetic protein 10

Gene ID

27302 (Human); 12154 (Mouse)

Uniprot ID

O95393 (Human); Q9R229 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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