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Creative Biolabs

Mouse Anti-Human PYK2 Monoclonal Antibody (CBP3979)

[CAT#: NAB2012924LS]

Anti-PYK2 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB

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Product Overview

Description

PYK2, also known as FAK2, is a non-receptor protein kinase. It is structurally similar to FAK, with 48% identity of amino acids, 60% identity of sequences in the central kinase domain, and identical positions of 4 phosphorylation sites. FAK is expressed ubiquitously, indispensable for embryogenesis, and colocalized at focal contacts with integrins and growth factor receptors. Expression of PYK2 is restricted to the endothelium, central nervous system, and hematopoietic lineages.

Immunogen

Purified recombinant fragment of PYK2 (aa 815-997) expressed in E. Coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3979

Applications

WB

Application Notes

WB (0.1-1.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

PYK2

Official Name

PTK2B

Full Name

PTK2B protein tyrosine kinase 2 beta

Alternative Names

PTK2B

Uniprot ID

Q14289(Human); Q9QVP9(Mouse); P70600(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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